I'd also like to make a tiny point for you guys. If you fit a heavy duty tubeless WIDE tire, you won'r get all the comfort that a softer non tubeless tire gives you. Not even close. It'll feel more like a hard pumped 2.125in tire when it comes to comfort (regardless of air pressure).
If you're a heavier rider looking to get more handling, grip, safety, mileage etc, sure run the tubeless. If your aim is comfort, stay away from it.